Helicobacter Pylori Infection Case Study

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Helicobacter pylori Infection as a Risk Factor for Coronary Artery Disease Enas Sh. Khater1* and Badawy A. Abdul Aziz2 1Department of Microbiology and Immunology, Faculty of Medicine, Benha University, Egypt. 2Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine, Benha University, Egypt. Authors’ contributions This work was carried out in collaboration between the two authors. Author ESK planned and designed the study, wrote the protocol, collected the samples, performed the practical laboratory activities, participated in the interpretation of the results and analysis, drafted and critically revised the manuscript. Author BAAA participated in planning and designing the study, sample collection, participated…show more content…
(4) Anonymous, University of Texas Health Science Center at Houston, Texas, USA. Complete Peer review History: http://sciencedomain.org/review-history/13813 Received 15th January 2016 Accepted 10th March 2016 Published 22nd March 2016 ABSTRACT Background: Helicobacter pylori (H. pylori) infection is the most common infection in the world and coronary artery disease (CAD) is probably associated with it. Aim: The aim of this prospective study was to evaluate the association between H. pylori infection and other risk factors with suspected CAD patients and to investigate the influence of H. pylori infection on cardiovascular risk factors (lipid profile and. Highly sensitive C-reactive protein (hs CRP) levels). Methods: Prospective cross sectional study was conducted to involve one hundred twenty patients with dyspeptic symptoms who involved 60 patients suffering from CAD and 60 controls…show more content…
The study was carried out for six months from June to - November 2015. H. pylori were detected by rapid urease test, H. pylori IgG ELISA test and Original Research Article Khater and Aziz; IJTDH, 15(2): 1-8, 2016; Article no.IJTDH.24342 2 histopathology. Total cholesterol (TC), high density lipoprotein cholesterol (HDL- c) and triglycerides (TG) were measured by enzymatic methods using an automated chemistry analyzer. Low density lipoprotein cholesterol (LDL- c) was calculated using the Friedewald equation. hs CRP levels were estimated. Results: H. pylori was confirmed in 80 (66.7%) of total 120 patients and controls by histology (gold method for diagnosis) and 80 (66.7%) by rapid urease test while 75 (62.5%) was detected by serology. There was no significant difference in age, sex or coronary artery risk factors between the two groups, but the prevalence of infectivity for H. pylori was higher in patients compared to controls (47{78.3%} versus 33 {55%} P 15 AU/ml (for adult patients) · NON IMMUNE (negative): when the anti-H. pylori IgG concentration is < 5 AU/ml · DOUBTFUL: if the result is between the two values. In this case it is advisable

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