Crohn's Disease Research Paper

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Crohn’s Disease Anatomy & Physiology Ashley Goodnight Crohn’s Disease Anatomy & Physiology Ashley Goodnight Abstract I am writing my paper on Crohn’s disease. In this paper you will find information on this disease and how people are affected. I will be explaining sign and symptoms, who may be at risk, and treatment options. Crohn’s disease is a chronic disorder of the digestive system. Crohn’s disease can affect any area of the gastrointestinal system from the mouth to the anus. Crohn’s disease appears to be caused by a dysfunctional inflammatory response in the gastrointestinal tract. Inflammation is the body’s natural way to heal by sending immune cells to the site of the injury or invader. Researchers…show more content…
Diagnosis is often made after a series of abdominal x-rays, an upper gastrointestinal series, or a colonoscopy. Endoscopy tests may include flexible sigmoidoscopy which allows the doctor to directly examine the colon with a lighted tube that is inserted through the anus. The mucosal layer of intestine that absorbs nutrition contains immune cells that act like defenders of the body. When this mucosal layer breaks down, harmful bacteria enter deep layers of the intestine. This results in inflammation causing swelling, increased blood flow, and ulcerations. In Crohn’s disease, these ulcerations go into the full thickness of the intestinal lining. This may lead to a narrowing of the bowel, which can lead to partial or total blockage of the intestinal flow, called bowel obstruction. Symptoms of intestinal obstruction include cramping around the mid-abdomen, frequently associated with vomiting. The abdomen may also become bloated and distended. Sores or ulcers within the intestinal tract are another complication. Deep ulcers can turn into fistulas that connect different parts of the intestine. Fistulas can tunnel into the surrounding areas such as the bladder, vagina, or skin. Proteins, calories, and vitamins are many times low for a patient with Crohn’s disease. Malnutrition or nutritional deficiencies are seen often in persons with Crohn’s disease. Malnutrition does not usually become a major problem unless the disease has gone untreated for an extensive

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