Fibrodysplasia Research Paper

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Fibrodysplasia is one of the most interesting diseases. A disease that basically causes bones to grow all over the body, due to sudden movement, injury, shots, etc. As the disease progresses the patient will begin to lose all function of their body until the only moving parts left are the eyes and lips. Fibrodysplasia ossificans progressiva (FOP), is an extremely rare disease effecting the connective tissues. Also known as Stone Man Syndrome, Fibrodysplasia is a mutation of the body’s repair mechanism that causes fibrous tissues such as muscle, tendon and ligament tissues to ossify (turn to bone) spontaneously or when damaged. Fibrodysplasia ossificans progressiva is an autosomal dominant disorder, mainly affecting those who are heterozygous…show more content…
Bone formation in patients with Fibrodysplasia ossificans progressiva happens when injured connective tissue or muscle cells at the injury or growth have the wrong enzyme present for bone repair during apoptosis (self-regulated cell death), resulting in lymphocytes containing large amounts of bone morphogenetic proteins. These bones are separate from the normal skeleton, forming its own skeletal elements. These elements can fuse together with normal skeletal bone. The diaphragm, tongue, and extra-ocular muscles aren’t effected, neither is cardiac and smooth muscle tissues. Because the disease is so rare, the symptoms are often misdiagnosed as cancer or fibrosis. Then leading doctors to preform biopsies, which actually exacerbate the growth of lumps. There is no known cure for Fibrodysplasia ossificans progressiva. Surgical attempts to remove the bone result in more spontaneous bone growth, also while under anesthesia, patients with Fibrodysplasia ossificans progressiva may have complications, which include difficulties with intubation, restrictive pulmonary disease, and changes in the electrical conduction system of the heart. Fibrodysplasia ossificans progressiva have to be extremely careful during any day-to- day activities, making sure no accidental damage is

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