Human Reproduction Essay

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The human reproduction cycle starts with the penetration of the penis into the vagina resulting in ejaculation of the spermatozoa. The spermatozoon then travels up the cervix through the uterus tract and into the ovary ducts with the help of chemotaxis following a gradient of progesterone secreted by cells surrounding the secondary oocyte, where a secondary oocyte from a graffian follicle is awaiting fertilization. Fertilization begins with the binding of a sperm head to the glycoprotein coating of the secondary oocyte called the zona pellucida. Exocytosis of the acrosome at the tip of the sperm head releases enzymes that digest a path through the zona and enable the sperm head to bind to the plasma membrane of the oocyte, as soon as this happens the secondary oocyte goes into meiosis stage two. When the spermatozoa fuses with the zona pellicuda it disintergrates leaving only the nucleus to enter the secondary oocyte, the secondary oocyte and the spermatozoa have 23 chromosomes each and when the nucleus enters the secondary oocyte it is now a secondary oocyte with 46 chromosomes. Soon the nucleus of the successful sperm enlarges into the male pronucleus. At the same time, secondary oocyte completes meiosis II forming a second polar body and the female pronucleus, it is now known as an ovum. The male and female pronuclei move toward each other while duplicating their DNA in S phase. Their nuclear envelopes disintegrate. A spindle is formed following replication of the sperm's centriole, and a full set of dyads assembles on it. The fertilized ovum now known as the zygote is now ready for its first mitosis. When this is done, 2 cells each with a diploid set of chromosomes are formed. Cleavage now happens which is a series of rapid mitotic divisions that subdivides the cytoplasm of the zygote into smaller, essentially equipotential cells called blastomeres contained

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